The previous meet record in the 100 was 11.27 set in 1998 by LSU's Kwajalein Butler. Finishing behind Brown was teammate Thompson in 11.29 while Danyel White finished fourth overall with an 11.54 that placed second in the next section of the event.
For Brown it was the fourth fastest time she has recorded and clearly the fastest she has generated in the month of March to open the outdoor season. Her 11.26 is the current world leader in the early stages of the outdoor season.
"Basically, I've been practicing as hard as I can," said Brown, who has a career best of 11.08 from 2015. "I just wanted to perform like I have been in practice. I was comfortable out there and when I heard them announce the meet record was 11.27 from 1998, I thought 'I need to get that.'
"In the race, everything was smooth, I didn't feel rushed. I felt like I was at practice. I got my confidence back and it was exciting."
In the 4x100 relay, the Aggie men won in a time of 39.13 seconds, which ranks fifth on the 2017 world list among early season marks and is the current U.S. and collegiate leader. The foursome included Will Williams, Fred Kerley, Elijah Morrow and Jace Comick.
Texas A&M won the race over Iowa (39.49), Arizona State (39.84), Ohio State (39.85), South Dakota (40.13) and Oklahoma (40.29). A second Aggie crew won the next section in 40.83 versus Iowa's 40.98 and placed seventh overall.
"We had some great performances here today," said Texas A&M head coach Pat Henry. "Coming off the NCAA Indoor Championships last week not everybody stepped on the track, but we still had a lot of people compete. It's that time for us to get the outdoor season going.
"With Aaliyah and Brenessa running 11.26 and 11.29 in the 100, that's getting up and getting after it. Aaliyah is much better at running 100m than 60m. It's just a better race for her."
In the women's sprint relay, Texas A&M's first group had a big lead, but did not get the final exchange made. A second group of Aggies placed third in 44.40 with a foursome of Kadecia Baird, Briyahna Desrosiers, Jaevin Reed and Glorilisha Carter. The first Texas A&M unit included White, Diamond Spaulding, Thompson, and Brown.
"I think we would have run something fast today in the relay, at least 43-low, even though we didn't have smooth handoffs on the earlier exchanges," noted Brown. "I still think we're going to run something pretty fast."
Jaevin Reed won the women's 400 in 53.43, moving to No. 12 on the Aggie all-time list. Reed put over a second on the rest of the field with Ohio State's Karrington Winters runner-up in 54.58. Oklahoma's Daye Shon Roberson did not finish.
The Aggies had a pair of runner-up performances in the discus. Jeff Bartlett turned in a toss of 186-5 to place second in the men's field, finishing behind Iowa's Reno Tuufuli, who won with a 193-8 (59.04).
Freshman Serena Brown hit a mark of 167-8 in the women's competition to place second to a 174-2 (53.10) by North Dakota's Katelyn Weimershirch. The effort by Brown moves her to No. 7 on the Texas A&M all-time list. Celine Markert finished seventh with a mark of 157-8 (48.07).
Other field events for Texas A&M included Emily Gunderson getting over 13-1 ¼ for second place in the pole vault, Garrett Cragin tying for third in the high jump with a 6-11 clearance, Kara Erickson clearing 508 ¾ for third place in the women's high jump, and Jeffrey Prothro placing fourth in the long jump with a leap of 24-3 ¼.
In the women's long jump the Aggie tandem of Ciynamon Stevenson (19-0 ½) and Lajarvia Brown (18-11 ¾) finished third and fifth. Sam Hardin (217-9) and William Petersson (217-2) teamed up to place fourth and fifth in the men's javelin.
At 800m, the Aggie trio entered in the women's race was led by Brittany Parker, who placed second with a 2:10.27 and moved to No. 11 on the Texas A&M all-time list. Miah Nelson followed in 2:10.78 to place fourth as Arin Rice clocked 2:12.16 for seventh place. In the men's race JaQwae Ellison posted a 1:50.31 to finish sixth as Gaines Kinsey ran 1:50.64 for ninth place.
Finishing on the track with the 4x400 the Aggie men ran 3:05.72 to establish an early outdoor collegiate leading time with a crew of Richard Rose, Eric Age, Elijah Morrow and Devin Dixon. A second Texas A&M crew, which consisted of Deon Hickey, Ilolo Izu, Infinite Tucker and Bryce Deadmon, clocked 3:10.23 to place fifth overall.
The Aggies finished behind a post-collegiate squad from Altis, who won in a world-leading 3:01.02 which also bettered the meet record of 3:03.20 set by Arizona State in 2001. The line-up for Altis included Dontavious Wright, Bralon Taplin, Paul Dedewo and Deon Lendore.
In the women's 4x400 relay, Texas A&M placed second with a time of 3:38.86 as they ran a foursome of Baird, Thompson, Carter and Lauren Lawless. Oklahoma won the race in 3:37.48.
Earlier in the meet Age was the top finisher for the Aggies in the men's 400 as he posted a time of 47.69 to place sixth. In the men's 100m, Seth Page finished sixth with a 10.58.